Identify
Pin down the right question before chasing answers.
The sharp question no one has yet posed.
What does not yet exist is always born there.
Find the signalhidden inside every body.
EEG, pulse waves, face, voice, hormones. IKI is a Tokyo-based research company recovering the subtle biosignals buried in noise — to build a new foundation for healthcare.
Domains / 05
KANSEISLEEPFACEVOICEHORMONE
Patents granted / pending Mission
Redefining richness through biomarkers.
People can only pursue what they can measure — which is why the world has long taken money and efficiency as its yardstick. From biosignals like brainwaves, pulse, expression and hormones, IKI turns what was never measurable before — happiness, sensibility, the states of mind and body — into biomarkers anyone can read. When the invisible becomes a measurable metric, both human choices and the very definition of richness begin to change.
Style 01 02 03
Kind
Measuring is never the goal in itself.
"Whose life, and for what, does this technology serve?" We refuse technical self-indulgence and stay fixed on enriching people's everyday lives.
That is what we mean by kindness.
Iterate
No answer is waiting to be found.
We refuse to be boxed in by conventional wisdom — try, verify, and try again.
Failure is just a waypoint. The answer is something we create beyond it.
Founder
Yasue Mitsukura
満倉 靖恵
- Founder & CEO, IKI Japan Inc. / IKI Inc.
- Professor, Faculty of Science and Technology, Keio University
- Concurrent Faculty, School of Medicine (Department of Neuropsychiatry), Keio University
Yasue Mitsukura is a biosignal-processing researcher and a professor at Keio University, with concurrent appointments in the Faculty of Science and Technology and the School of Medicine (Department of Neuropsychiatry). Her three-decade research program is built on a real-time noise-rejection algorithm — first patented in 1997 — that turns raw EEG and pulse waves into device-agnostic, comparable signals. On top of that foundation she has developed methods to estimate affect (KANSEI), sleep stages, cardiovascular trends, circulating hormones and early signs of dementia. Her work has appeared in Nature among other journals, and her affect-estimation invention was selected for the World Top-50 Inventions. In 2024 she founded IKI Japan Inc. to bring this research into the world.
Cut the noise.Keep the signal.
IKI begins with a real-time noise-rejection algorithm first patented in 1997. We separate signal from noise at the point of measurement, so that the data downstream is device-agnostic, comparable, and ready for biomarker inference.
01 — Capture
Capture
Acquire the subtle changes the body emits — EEG, pulse waves, video, mouth movement — from any device class.
02 — Cleanse
Cleanse
Separate noise in real time and align measurements across heterogeneous devices and environments.
03 — Infer
Infer
Layer state-estimation algorithms for affect, sleep, circulation, speech and hormones on top of a clean signal.
Different signals,one body.
Whatever the device or setting, the same body yields the same physiological readings. With its own noise-rejection algorithm as the common ground, IKI reads a range of biosignals — from EEG and pulse waves to camera footage and speech — on a single biomarker foundation.
01 KANSEI
Affect
Make moment-to-moment emotion visible — from brain waves and pulse, without a questionnaire.
02 SLEEP
Sleep stages
Five-stage sleep classification from a single pulse signal — no PSG, no electrodes.
03 FACE
Heart rate & blood pressure
Camera-only sensing. Read heart rate, HRV and blood-pressure trends from a face on screen.
04 VOICE
Silent speech
Read words from the mouth, even when there is no voice to hear.
05 HORMONE
Hormone levels
Track hormone dynamics from biosignals — without a needle, without a lab.
KANSEI Analyzer
感性アナライザMake the sensibility no one can put into words visible — read from the brain, once a second.
KANSEI Analyzer is the product form of IKI’s sensibility-estimation technology. Built on an EEG database and algorithms developed over roughly two decades, it makes interest, liking, focus, stress and calmness visible in real time — with nothing but a compact EEG headset and a tablet.
ESTIMATION RESULT
100500
0s30s60s90s120s
- Interest 72
- Liking 64
- Focus 81
- Stress 23
- Calmness 47
TIME 135s Export CSV
Beyond the five core metrics, the set extends to satisfaction, excitement, comfort and more — up to eight on request.
Highlights 01 02 03 04
Two decades of EEG data
Sensibility estimation grounded in ~20 years of EEG data and proprietary algorithms — metrics with academic backing.
The unspoken truth
Surface the latent, unconscious reactions a questionnaire can’t reach. Put a number on the “somehow”.
Anywhere, instantly
Just a small headset and a tablet. Low wearing burden, and noise rejection lets you measure even in the field.
Second-by-second
Capture five metrics in real time, synced to video or audio — so you can pinpoint the moment the mind moves.
Use cases
Evidence building
Prove the effect of foods, drinks, bathing or cosmetics with EEG — grounding PR and product claims.
Suntory / Rinnai / KOSÉAd & creative testing
Measure unconscious reactions to ads, packaging and content, and refine the creative.
Kanebo / SaizeriyaSpace & environment
Visualise how an office or store affects focus, stress and comfort.
Tokyu LandNeuromarketing
Capture the latent needs a survey can’t reach — a starting point for product and marketing.
Coca-Cola Japan / BridgestoneBuilt on academic,IP and clinical networks.
IKI Japan and IKI Inc. work in parallel — research, IP development and deployment, in service of a new healthcare foundation.
Nature
Published, Vol. 634 / Issue 8032
05+
Granted / pending patents
Top 50
World Top-50 Inventions
Keio × Stanford
Academic and clinical network
Entities
IKI Inc. / IKI Japan
- Name
- IKI Japan Inc.
- Global
- IKI Inc. (overseas, since Oct 2023)
- Founded
- Nov 29, 2024
- Stage
- Pre-Seed
- Location
- Tokyo, Japan
- Focus
- Preventive healthcare / biomarker discovery
History
History
- 1997 Founder Yasue Mitsukura is granted the initial patent for a real-time noise-rejection algorithm — the origin of IKI's core technology.
- Oct 2023 IKI Inc. (overseas entity) established.
- Oct 2024 Joint research published in Nature (Vol. 634 / Issue 8032).
- 20?? Affect-estimation invention selected for the World Top-50 Inventions.
- Nov 29, 2024 IKI Japan Inc. established.
04 — Contact
Bring the signalinto practice.
Joint research, PoCs, partnerships, hiring and media inquiries — including themes not yet ready for public disclosure — are welcome.